Description

16,17-Dehydro Capsaicin is a synthetic capsaicinoid analog, a potent and highly specific TRPV1 (Transient Receptor Potential Vanilloid 1) receptor agonist. This compound is of significant value for research and development due to its defined chemical structure and consistent bioactivity, making it a crucial tool for studying pain pathways, neurobiology, and thermoregulation. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on neurosensory and analgesic applications.

Application

• Neuroscience Research: As a selective TRPV1 channel agonist for studying pain sensation, neurogenic inflammation, and thermal hyperalgesia in preclinical models.
• Pharmacological Probe: Used in high-throughput screening (HTS) and assay development to identify and characterize novel TRPV1 antagonists or modulators.
• Analgesic Drug Development: Serves as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of next-generation topical pain relievers.
• Biochemical Studies: Investigation of receptor-ligand interactions, signal transduction pathways, and desensitization mechanisms related to the vanilloid receptor.
• Formulation Research: Used in the development and testing of transdermal delivery systems, patches, and creams designed for localized effect.

Basic Information

Product Name	16,17-Dehydro Capsaicin
CAS No.	509101-57-9
Molecular Formula	C18H27NO3
Molecular Weight	305.41 g/mol
Synonyms	16,17-Didehydrocapsaicin; (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide; Dehydrocapsaicin II; Synthetic Capsaicin Analog; TRPV1 Agonist; Vanilloid Receptor Agonist
EINECS	Contact for details

Quality Control

Our 16,17-Dehydro Capsaicin is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, and specifications can be provided to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.