Description

n-(3-Oxotetradecanoyl)-Dl-Homoserine Lactone is a synthetic homoserine lactone derivative, a key chemical class in quorum sensing research. This compound matters as a critical tool for studying and modulating bacterial cell-to-cell communication pathways, which govern virulence, biofilm formation, and other group behaviors. It is primarily needed by researchers and developers in the pharmaceutical, agricultural, and industrial biotechnology sectors for applications in anti-infective drug discovery, anti-biofilm strategies, and microbial process control.

Application

• Quorum Sensing Research: Acts as a molecular probe or inhibitor to study and disrupt bacterial communication systems in pathogens like Pseudomonas aeruginosa.
• Anti-Virulence Agent Development: Serves as a lead compound or intermediate in the synthesis of novel agents that attenuate bacterial pathogenicity without inducing strong selective pressure.
• Biofilm Inhibition Studies: Used in laboratory models to investigate and prevent the formation of persistent microbial biofilms on medical devices and industrial surfaces.
• Agricultural Biotechnology: Applied in research to interfere with quorum sensing in plant pathogens, offering a potential strategy for crop protection.
• Microbial Ecology: Utilized as a standard or reference compound in environmental studies of microbial community interactions.
• Academic & Pharmaceutical R&D: Essential for basic biological research and high-throughput screening campaigns targeting novel antibacterial mechanisms.

Basic Information

Product Name	n-(3-Oxotetradecanoyl)-Dl-Homoserine Lactone
CAS No.	503610-29-5
Molecular Formula	C18H31NO4
Molecular Weight	325.45 g/mol
Synonyms	N-Tetradecanoyl-3-oxo-DL-homoserine lactone; 3-Oxo-N-tetradecanoyl-DL-homoserine lactone; N-(3-Oxotetradecanoyl)homoserine lactone; C14-3-oxo-AHL; 3-Oxo-C14-HSL; Tetradecanoyl homoserine lactone, 3-oxo-; AHL C14:1 3-oxo; Pseudomonas aeruginosa autoinducer analog
EINECS	Contact for details

Quality Control

Our n-(3-Oxotetradecanoyl)-Dl-Homoserine Lactone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is hygroscopic and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 97%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.