Description

2,3,5-Tri-o-Butyryl-Myo-Inositol 1,4,6-Trisphosphate-Hexakis(Propionoxymethyl) Ester is a sophisticated, cell-permeable prodrug derivative of inositol trisphosphate (IP3), designed for advanced biochemical and pharmacological research. This compound is critical for studying intracellular calcium signaling pathways with high precision and minimal interference. It is an essential tool for researchers and developers in pharmaceutical discovery, molecular biology, and signal transduction studies who require reliable, high-purity chemical probes.

Application

• Intracellular Calcium Signaling Research: Used as a membrane-permeable precursor to deliver IP3 into cells for studying calcium release from endoplasmic reticulum stores.
• Pharmacological Probe Development: Serves as a key intermediate or tool compound in the development of drugs targeting phosphoinositide pathways.
• Biochemical Mechanism Studies: Employed to investigate the role of specific inositol phosphate isomers in cellular processes like metabolism, growth, and apoptosis.
• Academic and Industrial R&D: A vital reagent for basic research in university laboratories and for target validation in biotech and pharmaceutical companies.
• Diagnostic Assay Development: Can be utilized in the development of assays to measure phospholipase C activity or IP3 receptor function.

Basic Information

Item	Details
Product Name	2,3,5-Tri-o-Butyryl-Myo-Inositol 1,4,6-Trisphosphate-Hexakis(Propionoxymethyl) Ester
CAS No.	503158-17-6
Molecular Formula	C47H75O30P3
Molecular Weight	1213.0 g/mol (approx.)
Synonyms	IP3 Hexakis(Propionoxymethyl) Ester, Butyryl Derivative; myo-Inositol 1,4,6-trisphosphate, 2,3,5-tri-O-butyryl-, hexakis(propionoxymethyl) ester; D-myo-Inositol 1,4,6-trisphosphorothioate, 2,3,5-tri-O-butyryl-, hexakis(propionoxymethyl) ester (related analog); Cell-permeable IP3 analog; IP3-AM (Acetoxymethyl ester) analog; Inositol trisphosphate prodrug; caged IP3 precursor; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 2,3,5-Tri-o-Butyryl-Myo-Inositol 1,4,6-Trisphosphate-Hexakis(Propionoxymethyl) Ester is produced and handled under strict quality management protocols to ensure identity, purity, and stability for sensitive research applications. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with exacting research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.