Description

Fmoc-Asp(Otbu)-(Hmb)Gly-Oh is a protected amino acid derivative used as a key building block in solid-phase peptide synthesis (SPPS). This compound is specifically engineered to prevent unwanted side reactions during the assembly of complex peptides, ensuring high fidelity and yield. It is an essential raw material for research institutions and pharmaceutical companies developing therapeutic peptides, APIs, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a critical Fmoc-protected dipeptide unit for the controlled assembly of peptide chains.
• Pharmaceutical R&D: For the research and development of novel peptide-based Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Bioconjugation: Serving as a specialized linker or spacer molecule in the creation of peptide-protein or peptide-small molecule conjugates.
• Combinatorial Chemistry: Used in libraries for high-throughput screening to discover new bioactive compounds.
• Academic Research: A tool for studying peptide structure, function, and interactions in biochemistry and molecular biology laboratories.

Basic Information

Product Name	Fmoc-Asp(Otbu)-(Hmb)Gly-Oh
CAS No.	502640-94-0
Molecular Formula	C30H38N2O8
Molecular Weight	554.64 g/mol
Synonyms	Fmoc-Asp(OtBu)-(Hmb)Gly-OH; Fmoc-Asp(O-tert-butyl)-(2-hydroxy-4-methoxybenzyl)Gly-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-(2-hydroxy-4-methoxybenzyl)glycine; Fmoc-L-Asp(OtBu)-(Hmb)Gly-OH; Fmoc-Asp(OtBu)-Hmb-Gly-OH; Protected Fmoc-Asp-Gly derivative; Fmoc-Asp(OtBu)-(Hmb)-Glycine
EINECS	Contact for details

Quality Control

Every batch of Fmoc-Asp(Otbu)-(Hmb)Gly-Oh is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive peptide synthesis applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.