Description

(4R)-(+)-Hydroxy-2-Cyclopenten-1-One is a high-purity chiral building block and versatile synthetic intermediate. This compound matters for its role as a key precursor in the stereoselective synthesis of complex bioactive molecules, offering a defined stereocenter for downstream transformations. It is primarily needed by pharmaceutical R&D teams, fine chemical manufacturers, and academic researchers working on prostaglandins, nucleosides, and other chiral target molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of prostaglandin analogs and antiviral nucleosides.
• Asymmetric Synthesis: Used as a starting material for constructing complex natural products and active pharmaceutical ingredients (APIs) with high enantiomeric purity.
• Fine Chemical Production: Serves as a building block for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial Research: A valuable reagent in methodological development for new catalytic asymmetric reactions and total synthesis projects.
• Bioconjugate Chemistry: Potential use in modifying biomolecules due to its reactive carbonyl and hydroxyl functional groups.

Basic Information

Product Name	(4R)-(+)-Hydroxy-2-Cyclopenten-1-One
CAS No.	59995-47-0
Molecular Formula	C5H6O2
Molecular Weight	98.10 g/mol
Synonyms	(4R)-4-Hydroxy-2-cyclopenten-1-one; (R)-4-Hydroxy-2-cyclopenten-1-one; (+)-4-Hydroxy-2-cyclopenten-1-one; (R)-(+)-4-Hydroxy-2-cyclopentenone; 4R-Hydroxycyclopent-2-en-1-one; 4-Hydroxy-2-cyclopenten-1-one, (4R)-; (R)-4-Hydroxy-2-cyclopentenone
EINECS	Contact for details

Quality Control

Our (4R)-(+)-Hydroxy-2-Cyclopenten-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and purity assessment, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with full characterization data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.