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2,5-Dideoxy-2,5-Imino-D-Mannitol CAS NO 59920-31-9


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CAS No.:59920-31-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,5-Dideoxy-2,5-Imino-D-Mannitol is a high-purity iminosugar derivative, a valuable chiral building block and enzyme inhibitor. This compound is significant for its role in glycosidase inhibition, making it a critical intermediate in medicinal chemistry and biochemical research. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and fine chemical manufacturers focused on developing therapeutics for metabolic disorders and antiviral agents.

Application

  • Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of glycosidase inhibitors and antiviral drugs.
  • Biochemical Research: Used as a potent and selective inhibitor for studying enzyme mechanisms, particularly α-mannosidases and other glycosidases.
  • Glycobiology Studies: A crucial tool for probing carbohydrate-processing pathways and understanding related diseases.
  • Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new therapeutic candidates for diabetes, cancer, and viral infections.
  • Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.

Basic Information

Product Name 2,5-Dideoxy-2,5-Imino-D-Mannitol
CAS No. 59920-31-9
Molecular Formula C6H13NO4
Molecular Weight 163.17 g/mol
Synonyms 1,5-Dideoxy-1,5-imino-D-mannitol; DIM (2,5-Dideoxy-2,5-imino-D-mannitol); (2R,3R,4R,5R)-2,5-Bis(hydroxymethyl)piperidine-3,4-diol; 2,5-Dideoxy-2,5-iminomannitol; Iminosugar D-Mannitol derivative; 1-Deoxymannojirimycin isomer; Glycosidase inhibitor intermediate
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Quality Control

Our 2,5-Dideoxy-2,5-Imino-D-Mannitol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Chiral Purity ≥ 99.0% ee
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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