Description

(5β,12S,19β)-2,3-Didehydro-7α-Ethyl-8,20,21-Trinoraspidospermidine-3-Carboxylic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a sophisticated building block for the development of novel bioactive molecules. It is primarily required by research institutions and pharmaceutical R&D departments engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex natural product analogs and potential therapeutic agents.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and the design of new drug candidates targeting neurological and other disorders.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct intricate molecular architectures found in alkaloid chemistry.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Investigated for its interaction with biological targets and enzymes due to its complex aspidosperma-type skeleton.

Basic Information

Item	Detail
Product Name	(5β,12S,19β)-2,3-Didehydro-7α-Ethyl-8,20,21-Trinoraspidospermidine-3-Carboxylic Acid Methyl Ester
CAS No.	59871-84-0
Molecular Formula	C22H28N2O2
Molecular Weight	352.47 g/mol
Synonyms	Methyl (5β,12S,19β)-2,3-didehydro-7α-ethyl-8,20,21-trinoraspidospermidine-3-carboxylate; 7α-Ethyl-8,20,21-trinor-2,3-didehydroaspidospermidine-3-carboxylic acid methyl ester; Aspidospermidine derivative, 7α-ethyl-8,20,21-trinor-2,3-didehydro-, methyl ester; 3-Carbomethoxy-7α-ethyl-8,20,21-trinor-2,3-didehydroaspidospermidine; (5beta,12S,19beta)-2,3-Didehydro-7alpha-ethyl-8,20,21-trinoraspidospermidine-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by NMR, IR, and MS), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.