Description

Hemoglobin J Antakya is a naturally occurring variant of human hemoglobin, identified by its specific amino acid substitution. This biochemical is crucial for research into hemoglobinopathies and the structure-function relationships of oxygen transport proteins. It serves as a valuable reference standard and research reagent for clinical diagnostics, biochemical studies, and pharmaceutical development targeting blood disorders.

Application

• Biochemical Research: Used as a model protein for studying the effects of specific mutations on hemoglobin stability, oxygen affinity, and allosteric regulation.
• Clinical Diagnostics: Serves as a critical control or calibrator material in laboratory-developed tests (LDTs) and assays designed to detect and quantify hemoglobin variants.
• Hematology Reference Standards: Provides a characterized material for quality control in newborn screening programs and hemoglobin electrophoresis analysis.
• Pharmaceutical Development: Acts as a tool compound in drug discovery research aimed at modulating hemoglobin properties for therapeutic intervention in sickle cell disease or thalassemia.
• Academic & Educational Use: Employed in university and institutional settings for teaching advanced concepts in protein chemistry and molecular genetics.

Basic Information

Product Name	Hemoglobin J Antakya
CAS No.	59650-79-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb J-Antakya; Hemoglobin J Antakya; Hemoglobin variant J Antakya; α-2 12(A9)Lys->Asn β-2; Hb J (alpha12); Hemoglobin alpha chain variant J Antakya
EINECS	Contact for details

Quality Control

Our Hemoglobin J Antakya is produced and handled under stringent quality management protocols. Each batch is characterized using advanced analytical techniques to ensure identity, purity, and biological relevance. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), spectral identification, and physical state is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or desiccated conditions after each use to maintain stability.

Specification

Item	Specification
Appearance	Lyophilized powder or solid
Identification (IR / UV-Vis)	Conforms to reference spectrum
Purity (HPLC)	≥ 95% (Area %)
Protein Content (Biuret)	≥ 90%
Solubility	Soluble in aqueous buffers
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.