Description

(19E)-19,20-Didehydrocuran-17,18-Diol 17-Acetate CAS NO 59630-33-0 is a high-purity, semi-synthetic diterpenoid derivative. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a key synthetic intermediate or a reference standard. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of novel bioactive compounds, natural product chemistry, and pharmacological studies. Its defined structure makes it a valuable building block for medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex diterpenoid-based drug candidates.
• Reference Standard: Used as a high-purity analytical standard for quality control, method development, and identification in pharmaceutical and natural product analysis.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Natural Product Synthesis: A key intermediate in the total or semi-synthesis of curan and related diterpenoid natural products.
• Biochemical Research: Utilized in studies investigating enzyme interactions, biosynthetic pathways, and metabolic processes involving diterpenoid frameworks.

Basic Information

Product Name	(19E)-19,20-Didehydrocuran-17,18-Diol 17-Acetate
CAS No.	59630-33-0
Molecular Formula	C22H30O4
Molecular Weight	358.47 g/mol
Synonyms	19,20-Didehydrocuran-17,18-diol 17-acetate; (19E)-19,20-Didehydrocuran-17α,18-diol 17-acetate; 17-Acetoxy-19,20-didehydrocuran-17,18-diol; Curan-17,18-diol, 19,20-didehydro-, 17-acetate, (19E)-; A key diterpenoid intermediate.
EINECS	Contact for details

Quality Control

We supply (19E)-19,20-Didehydrocuran-17,18-Diol 17-Acetate in high-purity grades suitable for research and development. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to ensure batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.