Description

1-[cis-9-Octadecenoyl]-2-Hexadecanoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid with a defined acyl chain composition. This compound is a critical component for constructing biomimetic membranes and serves as a valuable standard in analytical chemistry and lipidomics research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise lipid structures for drug delivery systems, membrane studies, and diagnostic assay development.

Application

• Liposome & Nanoparticle Formulation: A key building block for creating stable, uniform liposomes used in drug delivery and vaccine adjuvants.
• Biomembrane Research: Used to create model membrane systems (e.g., vesicles, supported lipid bilayers) for studying membrane protein function, permeability, and fusion mechanisms.
• Analytical Standard: Serves as a certified reference material (CRM) for the quantification and identification of phosphatidylcholines in complex biological samples via HPLC-MS or GC-MS.
• Cell Culture & Media Supplement: Employed in specialized serum-free media formulations to support the growth of sensitive cell lines.
• Diagnostic Reagents: A component in the development of clinical diagnostic kits, particularly those involving enzymatic assays related to lipid metabolism.
• Biophysical Studies: Utilized in calorimetry (DSC), spectroscopy, and microscopy studies to investigate lipid phase behavior and membrane dynamics.

Basic Information

Product Name	1-[cis-9-Octadecenoyl]-2-Hexadecanoyl-Sn-Glycero-3-Phosphocholine
CAS No.	59491-62-2
Molecular Formula	C42H82NO8P
Molecular Weight	760.07 g/mol
Synonyms	POPC (1-Palmitoyl-2-Oleoyl-sn-glycero-3-phosphocholine); 1-Palmitoyl-2-oleoylphosphatidylcholine; (16:0-18:1) PC; 1-Palmitoyl-2-oleoyl-PC; Phosphatidylcholine, 1-palmitoyl-2-oleoyl-; 3-sn-Phosphatidylcholine, 1-hexadecanoyl-2-(9Z-octadecenoyl)-; 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1-[cis-9-Octadecenoyl]-2-Hexadecanoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0% (Area Percent)
Water Content (KF)	≤ 1.0 %
Solvent Residue (GC)	Meets ICH guidelines
Peroxide Value	≤ 3.0 mEq/kg
Phase Transition Temperature	-2 to 0 °C (by DSC)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.