Description

(5α,12β,19α)-2,3-Didehydro-21-Hydroxy-20-Oxoaspidospermidine-3-Carboxylic Acid Methyl Ester is a high-purity, complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical advanced intermediate for the development of novel bioactive molecules, particularly within the vinca alkaloid structural class. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new therapeutic agents or studying structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for novel anticancer and neurological drug candidates.
• Organic Synthesis Research: Used as a sophisticated precursor for constructing complex natural product analogs and heterocyclic compounds.
• Biochemical Tool Compound: Employed in pharmacological studies to investigate biological pathways and receptor interactions related to alkaloid activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Medicinal Chemistry: Integral for structure-activity relationship (SAR) studies aimed at optimizing potency and reducing toxicity in drug discovery programs.

Basic Information

Product Name	(5α,12β,19α)-2,3-Didehydro-21-Hydroxy-20-Oxoaspidospermidine-3-Carboxylic Acid Methyl Ester
CAS No.	59444-63-2
Molecular Formula	C22H24N2O4
Molecular Weight	380.44 g/mol
Synonyms	Methyl (5α,12β,19α)-2,3-didehydro-21-hydroxy-20-oxoaspidospermidine-3-carboxylate; Aspidospermidine-3-carboxylic acid, 2,3-didehydro-21-hydroxy-20-oxo-, methyl ester, (5α,12β,19α)-; 20-Oxoaspidospermidine-3-carboxylic acid methyl ester derivative; Dehydroaspidospermidine carboxylic acid methyl ester; 59444-63-2; Aspidospermine alkaloid intermediate
EINECS	Contact for details

Quality Control

Our (5α,12β,19α)-2,3-Didehydro-21-Hydroxy-20-Oxoaspidospermidine-3-Carboxylic Acid Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. All materials are characterized using advanced analytical techniques including HPLC, NMR, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.