Description

Alizapride Hydrochloride is a high-purity pharmaceutical active ingredient, a potent and selective dopamine D2 and serotonin 5-HT3 receptor antagonist. This compound is essential for the formulation of antiemetic medications, providing critical therapeutic effects. It is primarily required by pharmaceutical manufacturers and research institutions engaged in developing treatments for nausea and vomiting, particularly in oncology and post-operative care.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of injectable and oral antiemetic drugs.
• Key intermediate in advanced pharmaceutical research for central nervous system (CNS) disorders.
• Reference standard in analytical laboratories for quality control and method development.
• Biochemical research tool for studying dopaminergic and serotonergic receptor pathways.
• Formulation development for novel drug delivery systems targeting chemotherapy-induced nausea.

Basic Information

Product Name	Alizapride Hydrochloride
CAS No.	59338-87-3
Molecular Formula	C16H24ClN5O2 • HCl
Molecular Weight	406.76 g/mol
Synonyms	Alizapride HCl; 6-Methoxy-N-[(1-allyl-2-pyrrolidinyl)methyl]-1H-benzimidazol-2-amine Hydrochloride; N-[(1-Allyl-2-pyrrolidinyl)methyl]-6-methoxy-1H-benzimidazol-2-amine Hydrochloride; Litican; Plitican; Vergentan; (RS)-Alizapride Hydrochloride
EINECS	Contact for details

Quality Control

Our Alizapride Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for pharmaceutical use, including identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.