Description

(3A,5B,7A)-3-Hydroxy-7-(Sulfooxy)-Cholan-24-Oic Acid is a sulfated bile acid derivative, a key intermediate in the study of steroid metabolism and liver function. This compound matters for its role in biochemical research, particularly in the investigation of cholestasis, bile acid synthesis, and sulfotransferase enzyme activity. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on developing assays and therapeutic agents for hepatobiliary diseases.

Application

• Biochemical Research: Critical intermediate for studying bile acid sulfation pathways and steroid metabolism.
• Pharmaceutical Reference Standard: Used as a high-purity standard in the quality control and development of hepatobiliary drugs.
• Diagnostic Reagent Development: Serves as a key component in the formulation of clinical diagnostic kits for liver function and cholestatic disorders.
• Enzymology Studies: Employed as a substrate for sulfotransferase (SULT) enzyme assays to study enzyme kinetics and inhibition.
• Metabolite Identification: Used in LC-MS and NMR studies to identify and quantify sulfated bile acid metabolites in biological samples.
• Cell Culture & In Vitro Models: Applied in hepatocyte culture studies to model cholestatic injury and investigate cytoprotective mechanisms.

Basic Information

Product Name	(3A,5B,7A)-3-Hydroxy-7-(Sulfooxy)-Cholan-24-Oic Acid
CAS No.	59132-31-9
Molecular Formula	C24H40O7S
Molecular Weight	472.63 g/mol
Synonyms	7-Sulfooxy-3α-hydroxy-5β-cholan-24-oic Acid; Taurolithocholic Acid 7-Sulfate (partial); 3α-Hydroxy-7-sulfooxy-5β-cholan-24-oic Acid; 7-Sulfolithocholic Acid; Lithocholic Acid 7-Sulfate; 7-Sulfooxycholanic Acid; LCA-7S; 5β-Cholan-24-oic Acid, 3α-hydroxy-7-(sulfooxy)-, (3α,5β,7α)-
EINECS	Contact for details

Quality Control

Our (3A,5B,7A)-3-Hydroxy-7-(Sulfooxy)-Cholan-24-Oic Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.