Description

Bz-Ile-Glu-Gly-Arg-Pna CAS NO 59068-47-2 is a synthetic peptide substrate designed for high-precision biochemical research and diagnostic applications. Its core value lies in its specific cleavage by target proteases, making it an essential tool for enzyme activity assays and kinetic studies. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and in-vitro diagnostics (IVD) industries for developing and validating enzymatic tests.

Application

• Protease Activity Assays: Used as a chromogenic substrate to measure the activity and kinetics of specific proteolytic enzymes, including thrombin and other serine proteases.
• Biochemical Research: Serves as a critical reagent in studying enzyme mechanisms, inhibition, and substrate specificity in academic and industrial R&D laboratories.
• Diagnostic Kit Development: A key component in the formulation of colorimetric diagnostic kits for clinical testing, particularly in coagulation and fibrinolysis studies.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize potential protease inhibitor drug candidates.
• Quality Control in Biologics: Utilized to monitor and ensure the consistency and potency of enzyme-based biopharmaceutical products during manufacturing.

Basic Information

Product Name	Bz-Ile-Glu-Gly-Arg-Pna
CAS No.	59068-47-2
Molecular Formula	C30H43N9O9
Molecular Weight	649.72 g/mol
Synonyms	Benzoyl-Isoleucine-Glutamic Acid-Glycine-Arginine-p-Nitroanilide; Bz-Ile-Glu-Gly-Arg-pNA; Chromogenic Substrate H-D-Ile-Glu-Gly-Arg-pNA; Thrombin Substrate I; Tosyl-Gly-Pro-Arg-pNA Analog; S-2238 Analog; H-D-Ile-Glu(OBzl)-Gly-Arg-pNA; p-Nitroanilide Peptide Substrate
EINECS	Contact for details

Quality Control

Our Bz-Ile-Glu-Gly-Arg-Pna is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.