Description

(1S)-21-Norcycleanine CAS NO 59043-23-1 is a high-purity, specialized alkaloid compound of significant interest in advanced chemical synthesis and research. This product serves as a critical chiral building block and reference standard for the development of novel pharmaceutical agents and bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex natural products and therapeutic candidates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery programs.
• Biochemical Research: Used as a reference standard and pharmacological probe in studies investigating alkaloid biosynthesis, receptor interactions, and metabolic pathways.
• Asymmetric Synthesis: Employed as a sophisticated building block in stereoselective organic synthesis to construct complex molecular architectures with defined chirality.
• Natural Product Chemistry: Acts as a model compound or a synthetic target in the study, modification, and total synthesis of related isoquinoline and aporphine alkaloids.
• Analytical Standard: Provides a high-purity calibrant for analytical methods development and validation in quality control laboratories, including HPLC, LC-MS, and NMR analysis.

Basic Information

Product Name	(1S)-21-Norcycleanine
CAS No.	59043-23-1
Molecular Formula	C19H21NO3
Molecular Weight	311.38 g/mol
Synonyms	(1S)-21-Norcycleanine; (S)-21-Norcycleanine; Norcycleanine; 21-Norcycleanine; (1S)-6,6a,7-Trimethoxy-1,2,10,11-tetrahydro-4H-dibenzo[de,g]quinoline; (S)-6,6a,7-Trimethoxy-1,2,10,11-tetrahydro-4H-dibenzo[de,g]quinoline; (S)-Norcycleanine; (1S)-1,2,10,11-Tetrahydro-6,6a,7-trimethoxy-4H-dibenzo[de,g]quinoline
EINECS	Contact for details

Quality Control

Our (1S)-21-Norcycleanine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including chiral purity verification by HPLC, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.