Description

20-Ethyl-1α,16β-Dimethoxy-4-[[[2-(Acetylamino)Benzoyl]Oxy]Methyl]Aconitane-8,14α-Diol is a high-purity, structurally complex diterpenoid alkaloid derivative. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the study of novel bioactive molecules. It serves as a critical intermediate or reference standard for scientists in medicinal chemistry, pharmacology, and analytical laboratories requiring precise and reliable chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential new chemical entities (NCEs) for drug discovery programs.
• Reference Standard: Used as a high-purity calibration standard in analytical methods (e.g., HPLC, LC-MS) for quality control and research.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Biochemical Tool Compound: Utilized in in-vitro and ex-vivo studies to investigate specific biological pathways and mechanisms of action.
• Academic Research: A valuable compound for universities and research institutes studying natural product derivatives and alkaloid chemistry.
• Process Development: Acts as a model compound for developing and scaling up synthetic routes for complex alkaloid structures.

Basic Information

Product Name	20-Ethyl-1α,16β-Dimethoxy-4-[[[2-(Acetylamino)Benzoyl]Oxy]Methyl]Aconitane-8,14α-Diol
CAS No.	58969-45-2
Molecular Formula	C33H46N2O8
Molecular Weight	598.73 g/mol
Synonyms	4-[[[2-(Acetylamino)Benzoyl]Oxy]Methyl]-20-ethyl-1α,16β-dimethoxyaconitane-8,14α-diol; 8,14α-Dihydroxy-20-ethyl-1α,16β-dimethoxy-4-[[[2-(acetylamino)benzoyl]oxy]methyl]aconitane; Aconitane-8,14α-diol, 20-ethyl-1α,16β-dimethoxy-4-[[[2-(acetylamino)benzoyl]oxy]methyl]-; N-(2-((((1S,2R,3S,4R,5S,7S,8S,9R,10S,13S,16R,17S)-8-Ethyl-3,16-dimethoxy-11-methyl-6-oxapentacyclo[7.7.2.12,5.01,10.02,7]heptadecan-14-yl)oxy)carbonyl)phenyl)acetamide
EINECS	Contact for details

Quality Control

Our 20-Ethyl-1α,16β-Dimethoxy-4-[[[2-(Acetylamino)Benzoyl]Oxy]Methyl]Aconitane-8,14α-Diol is produced under a strict quality management system. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR, and MS for structural confirmation, to ensure identity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP standards for materials intended for research use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the certificate of analysis. This material is typically light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.