Description

n-Stearoyl-D-Sphingomyelin CAS NO 58909-84-5 is a high-purity, synthetic sphingomyelin derivative where the fatty acid moiety is stearic acid. This compound is a critical biochemical tool and a key building block for advanced lipid research and formulation. It is primarily utilized by research institutions and pharmaceutical companies engaged in membrane biophysics, lipidomics, and the development of lipid-based drug delivery systems such as liposomes and lipid nanoparticles (LNPs).

Application

• Biochemical & Biomedical Research: Essential for studying lipid raft formation, membrane fluidity, and cell signaling pathways.
• Lipid Nanoparticle (LNP) Formulation: Serves as a structural and functional lipid component in the development of advanced drug delivery vehicles for mRNA, siRNA, and other nucleic acid therapeutics.
• Liposome Preparation: Used to create model membranes and drug-loaded liposomes with specific biophysical properties for targeted delivery.
• Lipidomics Standards: Acts as a high-purity reference standard for the identification and quantification of sphingolipids in mass spectrometry-based lipidomic analyses.
• Cell Culture & Neuroscience Studies: Employed in specialized cell culture media and research focused on neuronal membrane structure and function.
• Cosmeceutical R&D: Investigated for its role in skin barrier function and as a bioactive ingredient in high-end skincare formulations.

Basic Information

Product Name	n-Stearoyl-D-Sphingomyelin
CAS No.	58909-84-5
Molecular Formula	C41H83N2O6P
Molecular Weight	731.08 g/mol
Synonyms	N-Stearoylsphingosylphosphorylcholine; D-erythro-Sphingosine, 1-stearoyl-; 1-Stearoyl-sn-glycero-3-phosphocholine (structural analog reference); SM(d18:1/18:0); Sphingomyelin (d18:1/18:0); N-(Octadecanoyl)-sphing-4-enine-1-phosphocholine; (2S,3R,4E)-2-Octadecanoylamino-4-octadecene-1,3-diol 1-Phosphocholine
EINECS	Contact for details

Quality Control

Our n-Stearoyl-D-Sphingomyelin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results from NMR, HPLC, and MS are provided and can be tailored to meet specific research or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is easily oxidized; it is recommended to store under an inert atmosphere (e.g., argon or nitrogen) after opening. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 98% (by weight)
Solubility	Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.