Description

Aculeacin A from Aspergillus aculeatus is a potent antifungal antibiotic complex derived from a specific fungal species. This compound is valued for its targeted activity against yeast and filamentous fungi, making it a critical reference standard and research tool. It is primarily utilized by pharmaceutical R&D teams, microbiologists, and quality control laboratories engaged in antifungal drug discovery and development.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and lead compound in the discovery and development of novel antifungal agents.
• Microbiological Studies: Used in in vitro assays to study fungal cell wall synthesis inhibition and mechanisms of antifungal action.
• Quality Control & Analytical Testing: Employed as a certified reference material (CRM) for the identification and potency testing of antifungal products.
• Academic Research: A vital tool in university and institutional labs for investigating fungal biology, pathogenesis, and resistance mechanisms.
• Biochemical Reagent: Used in enzymatic studies related to glucan synthesis, given its known mechanism as a glucan synthase inhibitor.

Basic Information

Product Name	Aculeacin A from Aspergillus aculeatus
CAS No.	58814-86-1
Molecular Formula	C72H111N5O24
Molecular Weight	1454.7 g/mol
Synonyms	Aculeacin A; Aculeacin; Antibiotic A 32204; Antibiotic A32204; A 32204; A32204; (3S,6R,7S,8S,9S,11R,12S,14R,16R,18S,19R)-19-[[(2S,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy]-14-[[(2R,5S,6S)-5-(dimethylamino)-6-methyloxan-2-yl]oxy]-3-[(1R)-1-hydroxyethyl]-18-methoxy-7,11,16-trimethyl-8,9,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthrene-4,9,12,15,17-pentone
EINECS	Contact for details

Quality Control

Our Aculeacin A is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, MS, NMR). A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain potency. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Biological Activity	Confirmed by antifungal assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.