Description

16-o-Acetylvindoline is a specialized alkaloid derivative, a key intermediate in the synthesis of complex pharmaceutical compounds. Its value lies in its role as a critical building block for research and development in medicinal chemistry, particularly for novel therapeutic agents. This high-purity compound is essential for pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on oncology and neurological drug discovery.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex vinca alkaloids and their analogs for anticancer research.
• Medicinal Chemistry Research: Used as a reference standard and a starting material for structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Biochemical Research: Employed in studies investigating tubulin binding and microtubule dynamics, relevant to cell division and cancer mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis using HPLC, LC-MS, or NMR.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis projects and pharmacological studies.
• Process Development: Acts as a key intermediate for scaling up and optimizing synthetic routes to valuable pharmaceutical targets in pilot plants.

Basic Information

Product Name	16-o-Acetylvindoline
CAS No.	58811-96-4
Molecular Formula	C25H32N2O6
Molecular Weight	456.53 g/mol
Synonyms	16-O-Acetylvindoline; Vindoline, 16-acetate; 16-Acetoxyvindoline; 16-Acetylvindoline; (3α,4β,5α,12α)-4-Acetoxy-3-ethyl-1,2,3,4,5,6,7,12-octahydro-5-hydroxy-7-methoxy-6-methyl-3,12-epoxy-6H-indolo[2,3-a]quinolizine-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 16-o-Acetylvindoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.