Description

1-Dehydrocorticosterone 21-Acetate is a synthetic steroid derivative, specifically an acetate ester of 1-dehydrocorticosterone. This compound is a key intermediate in the synthesis of more complex steroid hormones and is valued for its role in pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in steroid chemistry, anti-inflammatory drug discovery, and metabolic pathway studies.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of potent corticosteroid APIs (Active Pharmaceutical Ingredients).
• Biochemical Research: Used as a reference standard or precursor in studies investigating adrenal cortex hormone functions and metabolic pathways.
• Anti-inflammatory Agent Development: Serves as a structural template for developing novel glucocorticoid receptor modulators with potential therapeutic applications.
• Academic & Industrial R&D: Employed in laboratory-scale organic synthesis for method development and teaching advanced steroid chemistry.

Basic Information

Product Name	1-Dehydrocorticosterone 21-Acetate
CAS No.	58652-04-3
Molecular Formula	C23H30O5
Molecular Weight	386.48 g/mol
Synonyms	1-Dehydrocorticosterone Acetate; 21-Acetoxy-1,4-pregnadiene-11β,21-diol-3,20-dione; 11β,21-Dihydroxy-1,4-pregnadiene-3,20-dione 21-Acetate; 1,4-Pregnadiene-11β,21-diol-3,20-dione 21-Acetate; Cortisone 21-Acetate Derivative; 1-Dehydro Compound S Acetate; 11β-Hydroxyprogesterone 21-Acetate Derivative
EINECS	Contact for details

Quality Control

Our 1-Dehydrocorticosterone 21-Acetate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.