Description

[S,(-)]-1-O,2-o-Dipalmitoyl-D-Glycerol 3-Phosphoric Acid is a high-purity, enantiomerically pure phospholipid derivative, specifically a lysophosphatidic acid (LPA) analog with defined stereochemistry. This compound is critical for advanced research and development where precise molecular structure and biological activity are paramount. It serves as a key chiral intermediate and reference standard for pharmaceutical discovery, particularly in lipid signaling, metabolic pathway studies, and the development of targeted therapeutics.

Application

• Pharmaceutical Research & Development: As a chiral building block and reference standard for synthesizing novel lipid-based drugs and prodrugs.
• Biochemical Research: Used in the study of lysophosphatidic acid (LPA) receptor interactions, cell signaling pathways, and lipid metabolism.
• Lipidomics & Analytical Standards: Serves as a high-purity calibrant and internal standard in mass spectrometry and chromatographic analysis for lipid profiling.
• Drug Delivery Systems: Investigated as a functional component in liposomal and nanoparticle formulations for targeted delivery.
• Enzyme Substrate Studies: Employed as a specific substrate for phospholipases and other lipid-modifying enzymes in kinetic assays.

Basic Information

Product Name	[S,(-)]-1-O,2-o-Dipalmitoyl-D-Glycerol 3-Phosphoric Acid
CAS No.	58560-71-7
Molecular Formula	C35H69O8P
Molecular Weight	648.89 g/mol
Synonyms	(S)-1-O-Hexadecyl-2-O-hexadecanoyl-sn-glycero-3-phosphate; (S)-1-O-Palmitoyl-2-O-palmitoyl-sn-glycerol 3-phosphate; LPA(16:0/0:0) (S-isomer); sn-1-O-Alkyl-2-acyl-glycerol-3-phosphate; 1-O-Hexadecyl-2-palmitoyl-sn-glycero-3-phosphoric acid; (S)-LysoPA(16:0/0:0); 1-O-Alkyl-2-acyl-sn-glycerol-3-phosphate; 1-O-Palmitoyl-2-palmitoyl-sn-glycero-3-phosphate
EINECS	Contact for details

Quality Control

Our [S,(-)]-1-O,2-o-Dipalmitoyl-D-Glycerol 3-Phosphoric Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing specifications for identity, purity (by HPLC), chiral purity, and related substances. We adhere to cGMP principles for pharmaceutical intermediates, and our quality commitment ensures the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.