Description

4-Pentyn-2-ol 4-Methylbenzenesulfonate is a specialized organic compound that serves as a valuable building block and protecting group reagent in advanced synthetic chemistry. Its core value lies in its dual functionality, combining a reactive alkyne moiety with a tosylate leaving group, enabling precise molecular construction. This chemical is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring alkyne functionalization.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the creation of specialized polymers, dendrimers, and advanced organic materials.
• Cross-Coupling Reactions: Acts as a substrate in Sonogashira, Heck, and other palladium-catalyzed coupling reactions.
• Protecting Group Chemistry: The tosylate group can be used to protect alcohols in multi-step synthetic sequences.
• Ligand and Catalyst Development: Serves as a building block for creating novel ligands used in asymmetric catalysis.
• Academic & R&D Laboratories: A valuable tool for methodological development and exploring new chemical transformations in academic and industrial research settings.

Basic Information

Product Name	4-Pentyn-2-ol 4-Methylbenzenesulfonate
CAS No.	58456-48-7
Molecular Formula	C₁₂H₁₄O₄S
Molecular Weight	254.30 g/mol
Synonyms	4-Pentyn-2-ol Tosylate; 4-Pentyn-2-yl p-Toluenesulfonate; 2-Pentyn-4-ol Tosylate; 4-Methylbenzenesulfonic Acid 4-Pentyn-2-yl Ester; Tosyloxy-2-pentyne; 1-Methyl-3-butyn-1-yl p-Toluenesulfonate; 4-Pentyn-2-yl Tosylate
EINECS	Contact for details

Quality Control

Our 4-Pentyn-2-ol 4-Methylbenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our commitment to quality ensures reliable performance in your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.