Description

4'-Hydroxy-Delta(9)-Tetrahydrocannabinol is a hydroxylated derivative of the primary psychoactive cannabinoid, δ-9-THC. This compound is of significant interest in pharmaceutical and biomedical research due to its potential as a metabolite and its distinct pharmacological profile. It serves as a critical reference standard and intermediate for researchers and developers in the fields of analytical chemistry, cannabinoid pharmacology, and forensic science.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of cannabinoids and their metabolites in drug development and clinical research.
• Metabolite Studies: Essential for pharmacokinetic and metabolic pathway studies of δ-9-Tetrahydrocannabinol (THC) in both in vitro and in vivo models.
• Forensic Analysis: Serves as a certified reference material (CRM) for the accurate identification and confirmation of THC metabolites in forensic toxicology laboratories.
• Biochemical Research: Employed in receptor binding assays and studies investigating the structure-activity relationships (SAR) of cannabinoids.
• Method Development & Validation: A key component for developing and validating analytical methods such as HPLC, LC-MS/MS, and GC-MS for cannabinoid detection.
• Chemical Synthesis: Acts as a high-purity intermediate or starting material for the synthesis of novel cannabinoid analogs and derivatives.

Basic Information

Product Name	4'-Hydroxy-Delta(9)-Tetrahydrocannabinol
CAS No.	58434-43-8
Molecular Formula	C21H30O3
Molecular Weight	330.47 g/mol
Synonyms	4'-Hydroxy-δ9-THC; 4'-OH-δ9-THC; 4'-Hydroxytetrahydrocannabinol; 11-Hydroxy-δ9-tetrahydrocannabinol (isomeric); 11-OH-THC (common metabolite reference); 4'-Hydroxy-δ9-tetrahydrocannabinol; 4'-Hydroxy-trans-δ9-tetrahydrocannabinol
EINECS	Contact for details

Quality Control

Our 4'-Hydroxy-Delta(9)-Tetrahydrocannabinol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and reference standards. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, cool, and well-ventilated area. For long-term storage, consider storing under inert atmosphere to prevent potential oxidation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Research Grade)
Purity (HPLC)	≥ 98% (Analytical Reference Standard Grade)
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.