Description

4-Nitrophenol [1-14C] is a carbon-14 radiolabeled derivative of 4-nitrophenol, a key phenolic compound. This isotopically labeled version is essential for precise metabolic and environmental fate studies, enabling researchers to track the compound's pathway and degradation with high specificity. It is a critical tool for scientists in pharmaceutical research, agrochemical development, and environmental toxicology who require reliable tracers for advanced analytical applications.

Application

• Metabolic Pathway Tracing in pharmaceutical and agrochemical research to study drug or pesticide biotransformation.
• Environmental Fate Studies to monitor the degradation, adsorption, and leaching behavior of nitrophenol derivatives in soil and water systems.
• Enzyme Activity Assays, particularly as a substrate for hydrolytic enzymes like phosphatases and esterases, where the release of radiolabeled 4-nitrophenol is measured.
• Biochemical Research for investigating protein binding, transport mechanisms, and other molecular interactions.
• Analytical Method Development as an internal standard or tracer in advanced chromatographic (HPLC, LC-MS) and spectroscopic techniques.
• Toxicokinetic Studies to accurately determine the absorption, distribution, metabolism, and excretion (ADME) profile of related compounds.

Basic Information

Product Name	4-Nitrophenol [1-14C]
CAS No.	58402-66-7
Molecular Formula	C6H5NO3 (with 14C at position 1)
Molecular Weight	~139.11 g/mol (exact mass depends on specific activity)
Synonyms	p-Nitrophenol [1-14C]; 4-Hydroxynitrobenzene [1-14C]; 1-Hydroxy-4-nitrobenzene [1-14C]; PNP [1-14C]; 4-NP [1-14C]; 4-Nitrophenol (carbon-14 labeled); Radiolabeled 4-Nitrophenol; [1-14C]-4-Nitrophenol
EINECS	Contact for details

Quality Control

Every batch of 4-Nitrophenol [1-14C] is manufactured and analyzed under strict quality systems. We guarantee high chemical and radiochemical purity, with specifications typically including specific activity, radiochemical purity (by HPLC or TLC), and chemical purity. Comprehensive Certificates of Analysis (COA) detailing all analytical results are provided with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a designated area for radioactive materials. Ensure storage complies with all local and international regulations for handling and disposal of radiochemicals.

Specification

Item	Specification
Appearance	Yellow Crystalline Solid or Solution
Identification (IR/HPLC)	Conforms to Reference Standard
Specific Activity	Customizable (mCi/mmol)
Radiochemical Purity (HPLC)	≥ 97%
Chemical Purity (HPLC)	≥ 98%
Solvent (if supplied as solution)	Specified (e.g., Ethanol, Toluene)
Concentration	As per customer requirement

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.