Description

Colimecycline is a semi-synthetic tetracycline derivative with potent antibacterial activity. This compound is valued for its broad-spectrum efficacy against a range of Gram-positive and Gram-negative bacteria, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel antibiotic formulations and therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced antibiotic drugs and combination therapies.
• Antimicrobial Research: Used in microbiological and pharmacological research to study bacterial resistance mechanisms and develop new treatment protocols.
• Veterinary Medicine: Employed in the development of antibacterial treatments for livestock and companion animals.
• Reference Standard: Functions as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.
• Biochemical Studies: Applied in studies investigating protein synthesis inhibition and the mode of action of tetracycline-class antibiotics.

Basic Information

Item	Detail
Product Name	Colimecycline
CAS No.	58298-92-3
Molecular Formula	C₂₉H₃₈N₄O₈
Molecular Weight	570.64 g/mol
Synonyms	Colimeciclina; N-[(4-Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamido]methyl]-L-α-glutamine; Demeclocycline Methenamine; L-Glutamine, N-[(4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamido)methyl]-; Antibiotic U-24973A
EINECS	Contact for details

Quality Control

Our Colimecycline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets rigorous standards suitable for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept in a dry environment with minimal exposure to atmospheric moisture to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.