Description

(-)-Epicorynoxidine CAS NO 58000-48-9 is a specific stereoisomer of a natural isoquinoline alkaloid, valued for its role as a key chemical reference standard and a potential intermediate in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity, structurally defined molecules for method development and quality control in pharmaceutical and phytochemical applications. It is primarily sought by the pharmaceutical, nutraceutical, and academic research sectors for analytical and developmental purposes.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and purity testing of related alkaloids in drug development and quality control laboratories.
• Biochemical Research: Serves as a precise molecular tool for studying biological activity, metabolic pathways, and structure-activity relationships (SAR) of isoquinoline compounds.
• Natural Product Isolation & Analysis: Acts as a critical comparator in the isolation, characterization, and standardization of plant extracts and herbal formulations.
• Organic Synthesis Intermediate: Provides a chiral building block for the synthesis of more complex molecules in medicinal chemistry and fine chemical production.
• Analytical Method Development: Essential for developing and validating chromatographic methods (HPLC, LC-MS) in analytical laboratories.

Basic Information

Product Name	(-)-Epicorynoxidine
CAS No.	58000-48-9
Molecular Formula	C₁₉H₂₁NO₄
Molecular Weight	327.37 g/mol
Synonyms	(-)-Epicorynoxidine; Epicorynoxidine; (S)-Epicorynoxidine; 1,2,3,4-Tetrahydro-7-hydroxy-6-methoxy-1-[(4-hydroxyphenyl)methyl]-2-methylisoquinolin-8-ol; Corynoxidine (stereoisomer); Akuammiline analogue
EINECS	Contact for details

Quality Control

Our (-)-Epicorynoxidine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the stringent requirements for use as a reference material. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.