Description

(3β,16E,20β)-16,17,18,19-Tetradehydro-17-Methoxycorynan-16-Carboxylic Acid Methyl Ester is a high-purity, structurally complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical specialized intermediate for the development of novel therapeutic agents and complex natural product analogs. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of bioactive molecules targeting neurological and other disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex indole alkaloids and potential active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new drug candidates, particularly for central nervous system targets.
• Organic Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and validation in QC laboratories.
• Biochemical Research: Employed in studies investigating alkaloid biosynthesis pathways and biological activity.
• Fine Chemical Production: Utilized as a precursor for the custom synthesis of other specialized, high-value chemical entities.

Basic Information

Product Name	(3β,16E,20β)-16,17,18,19-Tetradehydro-17-Methoxycorynan-16-Carboxylic Acid Methyl Ester
CAS No.	57820-49-2
Molecular Formula	C22H24N2O3
Molecular Weight	364.44 g/mol
Synonyms	Methyl (3β,16E,20β)-16,17,18,19-tetradehydro-17-methoxycorynan-16-carboxylate; 17-Methoxy-16,17-didehydro-16-carbomethoxy-20β-yohimban; 17-Methoxy-16,17-didehydro-16-carbomethoxy-20β-heteroyohimban; 17-Methoxy-16,17-didehydro-16-carbonethoxy-20β-yohimban; 17-Methoxy-16,17-didehydro-16-carbonethoxy-20β-heteroyohimban; 17-Methoxy-16,17-didehydro-16-(methoxycarbonyl)-20β-yohimban; Alkaloid YC-2; YC-2
EINECS	Contact for details

Quality Control

Our (3β,16E,20β)-16,17,18,19-Tetradehydro-17-Methoxycorynan-16-Carboxylic Acid Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, generated using validated analytical methods such as HPLC, NMR, and MS. We support cGMP and ISO compliant manufacturing for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.