Description

Gtp(Gammaf) CAS NO 57817-57-9 is a high-purity chemical compound, also known as Guanosine-5'-triphosphate, γ-fluorinated analog. This modified nucleotide is a critical biochemical tool, offering enhanced stability and specific reactivity for advanced research applications. It is primarily utilized by biotechnology firms, pharmaceutical R&D departments, and academic research institutions engaged in enzymology, molecular biology, and nucleic acid chemistry.

Application

• Enzyme Kinetics & Mechanism Studies: Acts as a substrate or inhibitor for GTP-binding proteins (G-proteins) and GTPases to investigate enzymatic pathways.
• Nucleic Acid Research: Used in the synthesis and study of modified RNA transcripts to probe structure-function relationships.
• Biochemical Assay Development: Serves as a key component in high-throughput screening assays for drug discovery targeting nucleotide-dependent processes.
• Metabolic Pathway Analysis: A tool for tracing and analyzing energy transfer and signal transduction mechanisms within cells.
• Pharmaceutical R&D: Employed in the research of therapeutic agents that interfere with GTP-mediated cellular signaling.

Basic Information

Product Name	Gtp(Gammaf)
CAS No.	57817-57-9
Molecular Formula	C10H16FN5O14P3
Molecular Weight	559.16 g/mol
Synonyms	Guanosine-5'-triphosphate, γ-fluorinated; GTP-γ-F; Fluorinated GTP; 5'-Guanosyltriphosphate γ-fluoride; Guanosine 5'-(tetrahydrogen triphosphate), 1-(5-O-Phosphono-β-D-ribofuranosyl)-5-fluoro-1H-imidazo[4,5-d]pyrimidin-4-amine; γ-Fluoroguanosine triphosphate; Fluoroguanosine triphosphate
EINECS	Contact for details

Quality Control

Our Gtp(Gammaf) is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the exacting standards required for life science research. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.