Description

2-Bromo-6Beta-Fluoro-17,21-Dihydroxy-16Alpha-Methylpregna-1,4,9(11)-Triene-3,20-Dione 17,21-Di(Acetate) is a high-purity, synthetic steroid derivative with a complex halogenated structure, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in enabling the synthesis of novel therapeutic agents, particularly within the fields of endocrinology and anti-inflammatory drug discovery. This compound is essential for R&D chemists and process development scientists in pharmaceutical and fine chemical industries seeking to develop new steroid-based medications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel corticosteroid analogs and other potent steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry programs to explore structure-activity relationships (SAR) and develop new therapeutic candidates with anti-inflammatory or immunosuppressive properties.
• Process Chemistry: Serves as a standard or reference material in the development and optimization of scalable synthetic routes for complex steroid molecules.
• Academic Research: Utilized in university and institutional labs for studying steroid biochemistry, receptor interactions, and metabolic pathways.
• Fine Chemical Synthesis: Intermediate for creating specialized, high-value steroid derivatives used in various biological assays and testing.

Basic Information

Product Name	2-Bromo-6Beta-Fluoro-17,21-Dihydroxy-16Alpha-Methylpregna-1,4,9(11)-Triene-3,20-Dione 17,21-Di(Acetate)
CAS No.	57781-53-0
Molecular Formula	C₂₆H₃₀BrFO₆
Molecular Weight	537.42 g/mol
Synonyms	9(11)-Dehydro-6β-Fluoro-16α-Methylprednisolone 17,21-Diacetate 2-Bromo Derivative; 2-Bromo-6β-Fluoro-16α-Methylprednisolone 17,21-Diacetate; 2-Bromo-6β-Fluoro-16α-Methyl-1,4,9(11)-pregnatriene-17α,21-diol-3,20-dione 17,21-Diacetate; 2-Bromoflumethasone 17,21-Diacetate; Flumethasone 2-Bromo Derivative Diacetate; 6β-Fluoro-2-Bromo-16α-Methylprednisolone 17,21-Diacetate; NSC 134087
EINECS	Contact for details

Quality Control

Our 2-Bromo-6Beta-Fluoro-17,21-Dihydroxy-16Alpha-Methylpregna-1,4,9(11)-Triene-3,20-Dione 17,21-Di(Acetate) is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.