Description

Benclonidine is a potent and selective α-2 adrenergic receptor agonist, a key pharmaceutical intermediate and research compound. Its high specificity makes it a valuable tool for studying neurological pathways and developing therapeutic agents targeting hypertension, glaucoma, and opioid withdrawal symptoms. This compound is essential for pharmaceutical R&D laboratories, fine chemical synthesis units, and academic institutions engaged in neuropharmacology and cardiovascular research.

Application

• Pharmaceutical Intermediate: Critical synthesis block for the production of clonidine analogs and related antihypertensive agents.
• Neurological Research: Used as a reference standard and active compound in studies of α-2 adrenergic receptors in the central nervous system.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and method development in analytical laboratories.
• Preclinical Studies: Employed in animal models to investigate mechanisms of sedation, analgesia, and sympathetic nervous system modulation.
• Chemical Synthesis: A versatile building block for medicinal chemists to create novel derivatives with potential therapeutic applications.

Basic Information

Product Name	Benclonidine
CAS No.	57647-79-7
Molecular Formula	C13H16Cl2N4
Molecular Weight	299.20 g/mol
Synonyms	2,6-Dichloro-N-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine; 2-[(2,6-Dichloro-1,4-phenylenediamino)]-2-imidazoline; Benclonidine Hydrochloride (salt form); St-91; UK-14,304-18; B-HT 933; Azepexole; 2-(2,6-Dichloroanilino)-2-imidazoline
EINECS	Contact for details

Quality Control

Our Benclonidine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.