Description

1-Ethoxymethyl-5-Fluorouracil is a fluorinated pyrimidine derivative, a class of compounds of significant interest in pharmaceutical research and development. This compound serves as a key intermediate in the synthesis of more complex nucleoside analogs and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel anticancer and antiviral therapeutics, where precise chemical building blocks are essential.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of advanced fluoropyrimidine-based anticancer drugs and antiviral agents.
• Oncology Research: Used in preclinical and discovery research to develop new chemotherapeutic compounds targeting DNA synthesis.
• Nucleoside Chemistry: Serves as a modified base for creating novel nucleoside analogs with potential therapeutic activity.
• Biochemical Research: Employed in studies investigating enzyme inhibition, cell proliferation, and metabolic pathways.
• Process Development: Used by chemical development teams to scale up and optimize synthetic routes for API manufacturing.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	1-Ethoxymethyl-5-Fluorouracil
CAS No.	57610-22-7
Molecular Formula	C8H11FN2O3
Molecular Weight	202.18 g/mol
Synonyms	5-Fluoro-1-(ethoxymethyl)uracil; 1-(Ethoxymethyl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 5-Fluoro-1-ethoxymethyluracil; NSC 112907; EM-FU; 1-Ethoxymethyl-5-fluorouracil; 5-Fluorouracil, 1-(ethoxymethyl)-; 1-(Ethoxymethyl)-5-fluorouracil
EINECS	Contact for details

Quality Control

Our 1-Ethoxymethyl-5-Fluorouracil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and supply chain reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product should be kept under inert conditions if long-term stability is required. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.