Description

3α-[(5S,6S,7R)-5-Ethyl-1,2,3,4,5,6,7,8,9,10-Decahydro-6-Hydroxy-3,7-Methanoazacycloundecino[5,4-B]Indol-12-Yl]Vobasan-17-Oic Acid Methyl Ester is a complex indole alkaloid derivative with a highly specific stereochemistry, making it a valuable high-purity reference standard and advanced pharmaceutical intermediate. Its intricate polycyclic structure is of significant interest for research and development in medicinal chemistry. This compound is primarily required by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in drug discovery and development pipelines.
• Medicinal Chemistry Research: Serves as a key intermediate or building block for the synthesis of novel alkaloid-based drug candidates targeting central nervous system disorders.
• Biochemical Research: Employed in studies investigating the biological activity and structure-activity relationships (SAR) of complex natural product derivatives.
• Process Chemistry Development: Utilized in scaling up synthetic routes for the production of active pharmaceutical ingredients (APIs) in a GMP environment.
• Analytical Testing: Acts as a critical calibrant or system suitability standard in advanced chromatographic (HPLC, LC-MS) and spectroscopic analyses.

Basic Information

Product Name	3α-[(5S,6S,7R)-5-Ethyl-1,2,3,4,5,6,7,8,9,10-Decahydro-6-Hydroxy-3,7-Methanoazacycloundecino[5,4-B]Indol-12-Yl]Vobasan-17-Oic Acid Methyl Ester
CAS No.	57533-88-7
Molecular Formula	C31H38N2O4
Molecular Weight	502.65 g/mol
Synonyms	Vobasan-17-oic acid, 3α-[(5S,6S,7R)-5-ethyl-1,2,3,4,5,6,7,8,9,10-decahydro-6-hydroxy-3,7-methanoazacycloundecino[5,4-b]indol-12-yl]-, methyl ester; Methyl 3α-[(5S,6S,7R)-5-ethyl-1,2,3,4,5,6,7,8,9,10-decahydro-6-hydroxy-3,7-methanoazacycloundecino[5,4-b]indol-12-yl]vobasan-17-oate; 3α-Hydroxy-12-methoxyibogamine-17-carboxylic acid methyl ester (related structural class); A complex iboga-type alkaloid derivative.
EINECS	Contact for details

Quality Control

Our 3α-[(5S,6S,7R)-5-Ethyl-1,2,3,4,5,6,7,8,9,10-Decahydro-6-Hydroxy-3,7-Methanoazacycloundecino[5,4-B]Indol-12-Yl]Vobasan-17-Oic Acid Methyl Ester is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to verify stereochemical integrity. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.