Description

1-Pyrenebutyrylcholine is a specialized choline ester derivative featuring a pyrene fluorophore, making it a valuable biochemical tool. This compound is significant for its ability to serve as a fluorescent substrate or probe in enzymatic assays, particularly for studying cholinesterase activity. It is primarily needed by researchers and manufacturers in the fields of neuroscience, biochemistry, and diagnostic development for high-sensitivity detection and analytical applications.

Application

• Fluorescent Substrate for Cholinesterases: Used as a sensitive probe for acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activity assays in research and drug discovery.
• Biochemical Research: Employed in mechanistic studies of enzyme kinetics, inhibition, and reactivation processes.
• Diagnostic Kit Development: Serves as a key component in the formulation of fluorescent diagnostic kits for detecting cholinesterase levels in clinical or environmental samples.
• Neuropharmacology: Utilized in screening potential therapeutic agents targeting the cholinergic system.
• Cell-based Assays: Applied in live-cell imaging and histochemical staining to visualize enzymatic activity.
• Quality Control in Pharmaceutical Manufacturing: Acts as a reference standard or assay reagent for testing related pharmaceutical compounds.

Basic Information

Product Name	1-Pyrenebutyrylcholine
CAS No.	57440-79-6
Molecular Formula	C₂₅H₂₇NO₂
Molecular Weight	373.49 g/mol
Synonyms	Pyrenebutyrylcholine; N-(3-Carboxypropyl)-4-(1-pyrenyl)butyrylcholine; 4-(1-Pyrenyl)butyrylcholine; 1-Pyrenebutyric acid choline ester; Choline 1-pyrenebutyrate ester; PBC; Fluorogenic cholinesterase substrate
EINECS	Contact for details

Quality Control

Our 1-Pyrenebutyrylcholine is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectral analysis for structural confirmation, to ensure it meets the high standards required for research and diagnostic applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Fluorescence Properties	Conforms to typical profile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.