Description

(-)-Dihydroapovincaminic Acid Ethyl Ester is a high-purity, chiral organic compound belonging to the class of vinca alkaloid derivatives. This intermediate is of significant value in the research and development of advanced pharmaceutical agents, particularly those targeting neurological and cardiovascular systems. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions for the synthesis of novel therapeutic compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs), especially those derived from or related to vincamine alkaloids.
• Neurological Research: Used in the development and study of potential nootropic and cerebrovascular agents aimed at improving cognitive function and cerebral blood flow.
• Fine Chemical Synthesis: Serves as a critical precursor for the preparation of more complex, high-value specialty chemicals in multi-step synthetic routes.
• Reference Standard: Employed as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control testing of related substances.
• Academic & Industrial R&D: Utilized in chemical and pharmacological research to explore new structure-activity relationships and develop novel therapeutic candidates.

Basic Information

Product Name	(-)-Dihydroapovincaminic Acid Ethyl Ester
CAS No.	57327-92-1
Molecular Formula	C21H26N2O3
Molecular Weight	354.45 g/mol
Synonyms	Ethyl (-)-Dihydroapovincaminate; Dihydroapovincaminic Acid Ethyl Ester; (-)-Ethyl Dihydroapovincaminate; Apovincaminic Acid Ethyl Ester, Dihydro-; Vincamine Derivative; Eburnamenine-14-carboxylic acid, ethyl ester, (3alpha,16alpha)-; (3α,16α)-Eburnamenine-14-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our (-)-Dihydroapovincaminic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D and fine chemical synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.