Description

Ergocristine Methanesulfonate is a high-purity ergot alkaloid derivative, specifically the methanesulfonate salt of ergocristine. This compound is a critical intermediate and reference standard in advanced pharmaceutical research and development, valued for its precise biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of specialized therapeutics and in analytical method development.

Application

• Pharmaceutical Reference Standard: Used as a primary standard for the identification, assay, and purity testing of related ergot alkaloid APIs and formulations.
• Biochemical Research: Serves as a key reagent in studies investigating neurotransmitter receptor interactions, particularly within the dopaminergic and serotonergic systems.
• Active Pharmaceutical Ingredient (API) Synthesis: Acts as a crucial intermediate in the multi-step synthesis of complex therapeutic agents targeting neurological and cardiovascular conditions.
• Analytical Method Development: Employed in HPLC and LC-MS method validation for the accurate quantification of ergot alkaloids in complex matrices.
• Quality Control Laboratories: Essential for ensuring batch-to-batch consistency and regulatory compliance in the manufacturing of ergot-derived medicines.

Basic Information

Product Name	Ergocristine Methanesulfonate
CAS No.	57206-85-6
Molecular Formula	C35H41N5O7 • CH4O3S
Molecular Weight	707.81 g/mol
Synonyms	Ergocristine Mesylate; Ergocristine Methanesulphonate; 12'-Hydroxy-2',5'-α-(1-methylethyl)ergotaman-3',6',18-trione methanesulfonate; Dihydroergocristine methanesulfonate (related); Ergotaman-3',6',18-trione, 12'-hydroxy-2',5'-bis(1-methylethyl)-, (5'α)-, monomethanesulfonate; NSC 169015; UNII-9J9734Y4H5
EINECS	Contact for details

Quality Control

Our Ergocristine Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets the stringent requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.