Description

Nauclefine is a bioactive indole alkaloid isolated from plants of the *Nauclea* genus, recognized by the CAS registry number 57103-51-2. This compound is of significant interest for its potential pharmacological properties and serves as a key reference standard in analytical and research chemistry. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and natural product sectors for drug discovery, bioactivity studies, and quality control applications.

Application

• Pharmaceutical Research & Development: As a reference standard for the identification, purity assessment, and quantification of nauclefine in drug discovery pipelines and natural product extracts.
• Bioactivity & Pharmacological Studies: For in-vitro and in-vivo research investigating potential anti-inflammatory, antimicrobial, or anticancer properties.
• Analytical Chemistry: Used as a high-purity calibrant in chromatographic methods (HPLC, LC-MS) and spectroscopic analysis.
• Natural Product Isolation & Standardization: Serves as a benchmark compound for the standardization of herbal extracts and phytopharmaceutical products containing *Nauclea* species.
• Academic & Institutional Research: A critical tool for universities and research institutes studying plant alkaloids, their biosynthesis, and structure-activity relationships.

Basic Information

Product Name	Nauclefine
CAS No.	57103-51-2
Molecular Formula	C₂₁H₂₄N₂O₄
Molecular Weight	368.43 g/mol
Synonyms	Nauclefine; (19E)-Isositsirikine; 19,20-Didehydro-10,22-dioxoakuammiline; 16-Epi-19,20-didehydro-10,22-dioxoakuammiline; UNII-1C3A6R155U; 1C3A6R155U; Nauclefine (alkaloid); Nauclea diderrichii alkaloid
EINECS	Contact for details

Quality Control

Our Nauclefine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.