Description

11-Maleimidoundecanoic Acid is a bifunctional organic compound featuring a maleimide group and a terminal carboxylic acid, separated by a long alkyl chain. This structure makes it a highly valuable heterobifunctional crosslinking agent for the site-specific conjugation of biomolecules, such as proteins and peptides, to surfaces or other molecules. It is essential for researchers and manufacturers in the fields of bioconjugation, advanced material science, and diagnostic assay development who require precise and stable covalent linkages.

Application

• Bioconjugation Reagent: For the site-specific labeling of proteins, antibodies, and peptides via thiol-maleimide chemistry, enabling the creation of antibody-drug conjugates (ADCs) and diagnostic probes.
• Surface Functionalization: Used to modify gold nanoparticles, quantum dots, or polymer surfaces with a carboxylic acid-terminated linker for subsequent biomolecule immobilization.
• Hydrogel and Biomaterial Synthesis: Acts as a crosslinker in the development of functionalized hydrogels and polymeric scaffolds for tissue engineering and drug delivery systems.
• Affinity Chromatography Ligand: Employed to couple specific ligands to chromatographic resins for the purification of target biomolecules.
• Diagnostic Kit Component: Integral in the development of lateral flow assays and ELISA kits where stable covalent attachment of capture molecules is required.
• Polymer Modification: Serves as a functional monomer or modifier to introduce reactive maleimide groups into polymer backbones for advanced material applications.

Basic Information

Product Name	11-Maleimidoundecanoic Acid
CAS No.	57079-01-3
Molecular Formula	C15H23NO4
Molecular Weight	281.35 g/mol
Synonyms	N-(10-Carboxydecyl)maleimide; 11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoic Acid; Maleimidoundecanoic Acid; 1H-Pyrrole-1-undecanoic acid, 2,5-dihydro-2,5-dioxo-; 11-Maleimidoundecanoic acid; N-Maleimidoundecanoic acid; 10-(Maleimido)decanoic Acid; ω-Maleimidoundecanoic Acid
EINECS	Contact for details

Quality Control

Our 11-Maleimidoundecanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and bioconjugation applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, THF; slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.