Description

L-(-)-o-Tosyllactic Acid Ethyl Ester is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and functionalized structure make it a critical precursor for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), chiral catalysts, and specialized ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting neurological and metabolic disorders.
• Peptide Mimetics & Modifications: Used to introduce chiral, non-natural amino acid derivatives into peptide chains to enhance stability, bioavailability, and biological activity.
• Chiral Ligand & Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, agrochemicals, and specialty chemicals requiring high stereochemical purity.
• Academic & Process R&D: A valuable tool in research laboratories for method development in asymmetric synthesis and scaling up chiral synthetic routes.

Basic Information

Product Name	L-(-)-o-Tosyllactic Acid Ethyl Ester
CAS No.	57057-80-4
Molecular Formula	C₁₂H₁₆O₅S
Molecular Weight	272.32 g/mol
Synonyms	Ethyl (2S)-2-[(4-methylphenyl)sulfonyloxy]propanoate; (S)-(-)-Ethyl 2-[(p-toluenesulfonyl)oxy]propionate; L-(-)-Ethyl o-tosyl-lactate; L-(-)-α-Tosyloxypropionic Acid Ethyl Ester; (S)-Ethyl 2-(tosyloxy)propanoate; Ethyl L-(-)-o-tosyl-lactate; (S)-(-)-Ethyl 2-(p-toluenesulfonyloxy)propanoate
EINECS	Contact for details

Quality Control

Our L-(-)-o-Tosyllactic Acid Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) for every batch, detailing key parameters such as chiral purity (enantiomeric excess), chemical assay, and impurity profiles. Our quality commitment aligns with the standards required for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.