Description

Sodium Taurodehydrocholate is a high-purity conjugated bile acid salt, a critical biochemical reagent for advanced research and pharmaceutical development. Its primary value lies in its role as a potent surfactant and membrane-disrupting agent, facilitating the study of cellular processes and drug absorption. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors, particularly for applications requiring precise modulation of membrane permeability and solubility.

Application

• Pharmaceutical Research: Used as a key excipient and permeability enhancer in drug formulation studies, especially for poorly soluble active pharmaceutical ingredients (APIs).
• Cell Biology & Biochemistry: Serves as a critical reagent for membrane solubilization, protein extraction, and the study of bile acid transport mechanisms in vitro.
• Diagnostic Kits: Incorporated into enzymatic assay kits and diagnostic reagents as a stabilizing and activating agent for specific enzymes.
• Biochemical Standard: Utilized as a high-purity reference standard for analytical methods like HPLC and LC-MS in quality control laboratories.
• Lipid & Metabolic Studies: Applied in research models investigating cholesterol metabolism, liver function, and lipid digestion.

Basic Information

Product Name	Sodium Taurodehydrocholate
CAS No.	57011-24-2
Molecular Formula	C26H42NNaO7S
Molecular Weight	535.67 g/mol
Synonyms	Sodium Taurodehydrocholate; Taurodehydrocholic Acid Sodium Salt; Dehydrotaurocholic Acid Sodium Salt; 3α,7α-Dihydroxy-12-oxo-5β-cholan-24-oyltaurine Sodium Salt; N-(3α,7α-Dihydroxy-12-oxo-5β-cholan-24-oyl)taurine Sodium Salt; Sodium 2-[(3α,7α-dihydroxy-12-oxo-5β-cholan-24-oyl)amino]ethanesulfonate; TDCA-Na; TDHCA-Na
EINECS	Contact for details

Quality Control

Our Sodium Taurodehydrocholate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
pH (1% Solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.