Description

[8R,(-)]-5,8,13,13Aα-Tetrahydro-2,3,10-Trimethoxy-8α-Methyl-6H-Dibenzo[A,G]Quinolizine-11-Ol CAS NO 56974-41-5 is a high-purity, complex isoquinoline alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate stereochemistry and functional groups make it a valuable chiral building block and reference standard for the development of novel bioactive compounds. This product is essential for research and development laboratories in the pharmaceutical, biotechnology, and fine chemical sectors, where precise molecular structure and high purity are critical for successful outcomes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential therapeutic agents targeting neurological and cardiovascular systems.
• Biochemical Research: Used as a reference standard and probe in studies of alkaloid biosynthesis, enzyme inhibition, and receptor binding assays.
• Asymmetric Synthesis: Acts as a sophisticated chiral template or ligand in catalytic reactions to induce stereoselectivity.
• Academic & Discovery Chemistry: Employed in university and institutional labs for methodological development and the exploration of new chemical space within the isoquinoline family.
• Analytical Standard: Provides a certified reference material for quality control and method validation in analytical laboratories (HPLC, LC-MS).
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	[8R,(-)]-5,8,13,13Aα-Tetrahydro-2,3,10-Trimethoxy-8α-Methyl-6H-Dibenzo[A,G]Quinolizine-11-Ol
CAS No.	56974-41-5
Molecular Formula	C22H27NO4
Molecular Weight	369.46 g/mol
Synonyms	(-)-Corynoxine; (R)-(-)-Corynoxine; Corynoxine; 11-Hydroxycorynoxine; 8R-Corynoxine; 8R,13aα-Corynoxine; (8R,13aα)-5,8,13,13a-Tetrahydro-2,3,10-trimethoxy-8-methyl-6H-dibenzo[a,g]quinolizin-11-ol
EINECS	Contact for details

Quality Control

Our [8R,(-)]-Corynoxine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques. We adhere to relevant industry standards for fine chemicals, and specifications can be aligned with client requirements for specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.