Description

1,2-Di[trans-9-Octadecenoyl]-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid that serves as a critical building block for advanced lipid-based formulations. Its defined structure and high purity are essential for ensuring batch-to-batch consistency and performance in sensitive applications. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science sectors for developing liposomes, lipid nanoparticles (LNPs), and other biomimetic membranes.

Application

• Drug Delivery Systems: A key component in the formulation of liposomes and lipid nanoparticles (LNPs) for targeted and sustained release of active pharmaceutical ingredients (APIs).
• Biomembrane Research: Used as a standard or model phospholipid for studying membrane biophysics, permeability, and protein-lipid interactions.
• Cell Culture & Transfection: Employed in the preparation of lipid-based transfection reagents to facilitate the introduction of nucleic acids into cells.
• Diagnostic Reagents: Incorporated into the lipid bilayers of vesicles used in diagnostic assays and biosensors.
• Cosmetic & Dermal Formulations: Acts as an emollient and penetration enhancer in high-end cosmetic products designed for skin barrier repair.
• Nutritional Supplements: Used in advanced nutraceutical formulations where a specific, pure phospholipid source is required.

Basic Information

Product Name	1,2-Di[trans-9-Octadecenoyl]-Sn-Glycero-3-Phosphocholine
CAS No.	56782-46-8
Molecular Formula	C44H84NO8P
Molecular Weight	786.11 g/mol
Synonyms	1,2-Dioleoyl-sn-glycero-3-phosphocholine; DOPC; 1,2-Dioleoylphosphatidylcholine; (2R)-2,3-Bis[[(Z)-octadec-9-enoyl]oxy]propyl 2-(trimethylazaniumyl)ethyl phosphate; PC(18:1/18:1); L-α-Phosphatidylcholine, dioleoyl; Dioleoylphosphatidylcholine; 1,2-Di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1,2-Di[trans-9-Octadecenoyl]-Sn-Glycero-3-Phosphocholine is manufactured under strict quality systems to ensure it meets the exacting standards required for pharmaceutical and research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant cGMP and ISO 9001 guidelines to guarantee supply chain integrity and product traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and hydrolysis. For long-term storage, desiccate to protect against moisture. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Lyso-Impurity (HPLC)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%
Peroxide Value	≤ 3.0 meq/kg
Fatty Acid Composition (GC)	Conforms (C18:1 ≥ 95% of total fatty acids)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.