Description

(3β,16E)-16,17-Didehydro-9-Hydroxy-17-Methoxy-2-Oxocorynoxan-16-Carboxylic Acid Methyl Ester is a high-purity, semi-synthetic oxindole alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of complex bioactive molecules targeting neurological and metabolic pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) drug discovery.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing (HPLC, LC-MS).
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Biochemical Research: Investigated for its potential interactions with various enzymes and receptors in pharmacological assays.
• Academic Studies: Serves as a model compound in advanced organic chemistry and natural product synthesis research.
• Process Development: Used in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs).

Basic Information

Item	Detail
Product Name	(3β,16E)-16,17-Didehydro-9-Hydroxy-17-Methoxy-2-Oxocorynoxan-16-Carboxylic Acid Methyl Ester
CAS No.	56687-49-1
Molecular Formula	C21H24N2O5
Molecular Weight	384.43 g/mol
Synonyms	9-Hydroxy-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester; Corynoxan-16-carboxylic acid derivative; Oxindole alkaloid derivative; Methyl (3β,16E)-16,17-didehydro-9-hydroxy-17-methoxy-2-oxocorynoxan-16-carboxylate; 16-Carbomethoxycorynoxan derivative
EINECS	Contact for details

Quality Control

Our (3β,16E)-16,17-Didehydro-9-Hydroxy-17-Methoxy-2-Oxocorynoxan-16-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.