Description

8-Benzylthio-N(6)-n-Butyladenosine Cyclic-3,5'-Monophosphate is a chemically modified derivative of cyclic adenosine monophosphate (cAMP), a crucial secondary messenger in cellular signaling pathways. This compound is engineered for enhanced membrane permeability and resistance to enzymatic degradation, making it a powerful tool for modulating intracellular cAMP levels. It is primarily utilized by researchers in pharmaceutical development, biochemistry, and molecular biology for studying signal transduction, as well as by manufacturers in the fine chemical and life science reagent sectors.

Application

• Biochemical Research: A key tool for studying cAMP-dependent protein kinase (PKA) activation and downstream signaling cascades in cell-based assays.
• Pharmaceutical R&D: Used as a reference standard and a cell-permeable agonist in drug discovery programs targeting G-protein-coupled receptors (GPCRs) and metabolic disorders.
• Signal Transduction Studies: Investigates the role of cAMP in processes like gene expression, ion channel function, and cellular metabolism.
• Enzyme Inhibition Studies: Serves as a stable, cell-permeable analog to study phosphodiesterase (PDE) activity and inhibition.
• Life Science Reagents: A critical component in assay kits and research reagents for academic and industrial laboratories.
• Fine Chemical Synthesis: Used as a sophisticated building block or intermediate in the synthesis of more complex bioactive molecules.

Basic Information

Product Name	8-Benzylthio-N(6)-n-Butyladenosine Cyclic-3,5'-Monophosphate
CAS No.	56583-64-3
Molecular Formula	C21H26N5O6PS
Molecular Weight	507.50 g/mol
Synonyms	8-Benzylthio-N6-n-butyladenosine 3',5'-cyclic monophosphate; 8-Benzylthio-Bt2-cAMP; 8-BnS-Bt2-cAMP; 8-Benzylthio-N6-butyladenosine-3',5'-cyclic monophosphate; Bt2-8-BnS-cAMP; 8-Benzylthio-N6-butyl-cAMP; cAMP analog, 8-benzylthio-N6-butyl-; 8-Benzylthio-N(6)-butyladenosine cyclic 3',5'-hydrogen phosphate
EINECS	Contact for details

Quality Control

Our 8-Benzylthio-N(6)-n-Butyladenosine Cyclic-3,5'-Monophosphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.