Description

6-Hydroxy-2,5,7,8-Tetramethylchroman-2-Carboxylic Acid is a high-purity synthetic antioxidant compound, widely recognized as a key intermediate in the production of Trolox, a water-soluble analog of Vitamin E. This compound is valued for its potent radical-scavenging properties and stability, making it a critical component in advanced formulations. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and high-performance cosmetic industries seeking to enhance product shelf-life and efficacy.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of Trolox, a standard antioxidant used in biomedical research and as a reference compound.
• Nutraceutical & Dietary Supplements: Incorporated into formulations for its potent antioxidant activity, supporting cellular health and product stability.
• Cosmetic & Personal Care: Used in anti-aging serums, creams, and sunscreens to protect skin from oxidative stress and free radical damage.
• Biochemical Research: Serves as a standard or reagent in studies of lipid peroxidation, oxidative stress, and antioxidant mechanisms.
• Food & Beverage Preservation: Employed as a stabilizing agent in high-value food products and beverages to prevent rancidity and spoilage.
• Polymer & Material Science: Acts as an antioxidant additive in specialty polymers and coatings to inhibit degradation and extend material lifespan.

Basic Information

Product Name	6-Hydroxy-2,5,7,8-Tetramethylchroman-2-Carboxylic Acid
CAS No.	56305-04-5
Molecular Formula	C14H18O4
Molecular Weight	250.29 g/mol
Synonyms	Trolox Intermediate; 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid; 2-Carboxy-2,5,7,8-tetramethyl-6-chromanol; 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid; Vitamin E water-soluble analog intermediate; Aldrich 238813; Chroman-2-carboxylic acid, 6-hydroxy-2,5,7,8-tetramethyl-
EINECS	260-106-1

Quality Control

Our 6-Hydroxy-2,5,7,8-Tetramethylchroman-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and nutraceutical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.