Description

(16R)-17-Hydroxy-10-Methoxy-2,4(1H)-Cyclo-3,4-Secoakuammilan-16-Carboxylic Acid Methyl Ester is a high-purity, structurally complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and a valuable reference standard for the development of novel bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on alkaloid chemistry, medicinal chemistry, and process development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly those targeting neurological and metabolic pathways.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development, validation, and compound identification via HPLC, LC-MS, or NMR.
• Medicinal Chemistry Research: Provides a core scaffold for structure-activity relationship (SAR) studies and the synthesis of novel indole alkaloid analogs for biological screening.
• Academic & Industrial R&D: Employed in synthetic organic chemistry projects exploring complex natural product synthesis, asymmetric synthesis, and novel heterocyclic compound libraries.
• Biochemical Research: Potential use as a tool compound in biochemical assays to study enzyme interactions or receptor binding where specific alkaloid structures are required.

Basic Information

Product Name	(16R)-17-Hydroxy-10-Methoxy-2,4(1H)-Cyclo-3,4-Secoakuammilan-16-Carboxylic Acid Methyl Ester
CAS No.	56259-11-1
Molecular Formula	C21H26N2O4
Molecular Weight	370.45 g/mol
Synonyms	Methyl (16R)-17-hydroxy-10-methoxy-2,4(1H)-cyclo-3,4-secoakuammilan-16-carboxylate; 10-Methoxy-17-hydroxyakuammilan-16-carboxylic acid methyl ester (16R stereoisomer); Secoakuammilan alkaloid derivative; Indole alkaloid intermediate; (16R)-AKU derivative; 56259-11-1; 17-Hydroxy-10-methoxy-secoakuammilan-16-methyl carboxylate
EINECS	Contact for details

Quality Control

Our (16R)-17-Hydroxy-10-Methoxy-2,4(1H)-Cyclo-3,4-Secoakuammilan-16-Carboxylic Acid Methyl Ester is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP and ISO compliant documentation for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.