Description

Dansyl-D-Phenylalanine Free Acid is a high-purity, chiral dansyl-labeled derivative of the essential amino acid phenylalanine. This compound is a critical reagent in advanced analytical and biochemical research, valued for its strong fluorescence properties and stereochemical specificity. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and academic sectors for applications requiring precise chiral analysis and fluorescence-based detection.

Application

• Chiral Chromatography Standard: Serves as a reference standard for method development and validation in High-Performance Liquid Chromatography (HPLC) to separate and quantify enantiomers.
• Fluorescent Labeling & Derivatization: Used to tag peptides, amino acids, or other biomolecules to enhance their detectability in sensitive fluorescence assays.
• Biochemical Research: Acts as a substrate or probe in enzymatic studies, receptor-ligand binding assays, and metabolic pathway investigations.
• Pharmaceutical Analysis: Employed in the quality control of chiral drug substances and intermediates to ensure enantiomeric purity.
• Proteomics & Peptide Chemistry: Utilized in the synthesis and analysis of modified peptides for structural and functional studies.
• Academic & Institutional Research: A key tool in university and institutional labs for teaching and advanced research in analytical chemistry and biochemistry.

Basic Information

Product Name	Dansyl-D-Phenylalanine Free Acid
CAS No.	56176-31-9
Molecular Formula	C21H22N2O4S
Molecular Weight	398.48 g/mol
Synonyms	5-(Dimethylamino)naphthalene-1-sulfonyl-D-phenylalanine; Dansyl-D-Phe-OH; D-2-(5-Dimethylaminonaphthalene-1-sulfonamido)-3-phenylpropanoic Acid; N-[(5-Dimethylamino-1-naphthalenyl)sulfonyl]-D-phenylalanine; DNS-D-Phenylalanine
EINECS	Contact for details

Quality Control

Our Dansyl-D-Phenylalanine Free Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling by HPLC, to ensure it meets the stringent requirements for research and analytical applications. A detailed Certificate of Analysis (COA) providing batch-specific data is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.