Description

4Alpha-Phorbol-12,13-Diacetate is a phorbol ester derivative, a class of compounds known for their potent biological activity and role as protein kinase C (PKC) activators. This high-purity compound is critical for biochemical and pharmacological research, particularly in the study of cell signaling pathways, tumor promotion, and inflammation. It is an essential tool for researchers and laboratories in the pharmaceutical, biotechnology, and academic sectors requiring reliable and well-characterized biochemical probes.

Application

• Biochemical Research: Used as a potent and specific activator of Protein Kinase C (PKC) isoforms in signal transduction studies.
• Pharmacological Studies: Employed in research on tumor promotion, inflammation, and immune response mechanisms.
• Cell Biology: A key tool for investigating cell proliferation, differentiation, and apoptosis pathways.
• Drug Discovery: Serves as a reference standard and a molecular probe in screening assays for PKC-targeted therapeutics.
• Toxicology: Used in studies examining the mechanisms of action of tumor-promoting agents.
• Academic & Institutional Research: Essential for universities and research institutes conducting advanced studies in molecular biology and cancer research.

Basic Information

Product Name	4Alpha-Phorbol-12,13-Diacetate
CAS No.	56144-62-8
Molecular Formula	C28H38O8
Molecular Weight	502.60 g/mol
Synonyms	4α-Phorbol 12,13-Diacetate; Phorbol 12,13-Diacetate; 4α-PDD; 4-α-Phorbol-12,13-Diacetate; NSC 168807; 12,13-Diacetoxy-4alpha-phorbol; 4α-Phorbol-12α,13α-diacetate; 4α-Phorbol Diacetate
EINECS	Contact for details

Quality Control

Our 4Alpha-Phorbol-12,13-Diacetate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques, including HPLC and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.