Description

(5α,12β,19α,20R)-1-Formyl-8-Oxo-2α,20-Cycloaspidospermidine-3β-Carboxylic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and key synthetic intermediate for the development of novel pharmaceutical agents and bioactive molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the synthesis of complex natural products and the development of new therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of complex indole alkaloids and potential drug candidates.
• Organic Synthesis Research: Used as a sophisticated building block for constructing complex molecular architectures in academic and industrial R&D settings.
• Natural Product Synthesis: Essential for the total or semi-synthesis of biologically active natural products derived from the aspidosperma alkaloid family.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new compounds with targeted biological activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry Development: Used in scaling up synthetic routes for the production of active pharmaceutical ingredients (APIs).

Basic Information

Item	Detail
Product Name	(5α,12β,19α,20R)-1-Formyl-8-Oxo-2α,20-Cycloaspidospermidine-3β-Carboxylic Acid Methyl Ester
CAS No.	56086-67-0
Molecular Formula	C23H26N2O4
Molecular Weight	394.47 g/mol
Synonyms	1-Formyl-8-oxo-2α,20-cycloaspidospermidine-3β-carboxylic acid methyl ester; Methyl (5α,12β,19α,20R)-1-formyl-8-oxo-2α,20-cycloaspidospermidine-3β-carboxylate; 2α,20-Cycloaspidospermidine-3β-carboxylic acid, 1-formyl-8-oxo-, methyl ester, (5α,12β,19α,20R)-; Aspidospermidine derivative; Indole alkaloid intermediate.
EINECS	Contact for details

Quality Control

Our (5α,12β,19α,20R)-1-Formyl-8-Oxo-2α,20-Cycloaspidospermidine-3β-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.