Description

(3β,5α,12β,19α,20R)-1-Acetyl-6,7-Didehydro-3-Methyl-2α,20-Cycloaspidospermidine CAS NO 56053-36-2 is a high-purity, structurally complex indole alkaloid derivative, valued for its role as a critical synthetic intermediate and reference standard in advanced pharmaceutical research. This compound is essential for the development and quality control of novel therapeutic agents, particularly in oncology and neurological research. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex indole-based drug candidates and natural product analogs.
• Reference Standard: Used for analytical method development, validation, and quality control (HPLC, LC-MS) in pharmaceutical manufacturing and regulatory compliance.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to explore new biological activities and optimize drug properties.
• Academic Research: Employed in university and institutional labs for studying alkaloid biosynthesis, chemical synthesis pathways, and novel reaction methodologies.
• Biochemical Tool Compound: Potential use in probing specific biological pathways and target interactions due to its defined stereochemistry and functional groups.

Basic Information

Product Name	(3β,5α,12β,19α,20R)-1-Acetyl-6,7-Didehydro-3-Methyl-2α,20-Cycloaspidospermidine
CAS No.	56053-36-2
Molecular Formula	C22H28N2O
Molecular Weight	336.47 g/mol
Synonyms	1-Acetyl-6,7-didehydro-3-methyl-2α,20-cycloaspidospermidine; Aspidospermidine, 1-acetyl-6,7-didehydro-3-methyl-2α,20-cyclo-; 2α,20-Cycloaspidospermidine, 1-acetyl-6,7-didehydro-3-methyl-; (3beta,5alpha,12beta,19alpha,20R)-1-Acetyl-6,7-didehydro-3-methyl-2alpha,20-cycloaspidospermidine; 56053-36-2; Cycloaspidospermidine derivative
EINECS	Contact for details

Quality Control

Our (3β,5α,12β,19α,20R)-1-Acetyl-6,7-Didehydro-3-Methyl-2α,20-Cycloaspidospermidine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC purity assay, identity confirmation (IR, MS), and residual solvent analysis to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.