Description

(5α,12β,19α,20R)-6,7-Didehydro-1-Methyl-2α,20-Cycloaspidospermidine-3β-Methanol Acetate is a complex, high-purity indole alkaloid derivative with a unique cyclized aspidospermidine core structure. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the synthesis of novel bioactive molecules and as a key chiral intermediate. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the exploration of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the multi-step synthesis of potential drug candidates, especially those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used as a reference standard or a starting material for structure-activity relationship (SAR) studies to develop new alkaloid-based therapeutics.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of complex natural product analogs.
• Biochemical Research: May be utilized in studies investigating the interaction of alkaloids with biological targets such as receptors or enzymes.
• Academic Research: Used in university and institutional labs for synthetic organic chemistry projects and the study of alkaloid synthesis methodologies.

Basic Information

Product Name	(5α,12β,19α,20R)-6,7-Didehydro-1-Methyl-2α,20-Cycloaspidospermidine-3β-Methanol Acetate
CAS No.	56053-30-6
Molecular Formula	C22H28N2O2
Molecular Weight	352.47 g/mol
Synonyms	1-Methyl-2α,20-cycloaspidospermidine-3β-methanol, 6,7-didehydro-, acetate (ester), (5α,12β,19α,20R)-; 2α,20-Cycloaspidospermidine-3β-methanol, 6,7-didehydro-1-methyl-, acetate, (5α,12β,19α,20R)-; Aspidospermidine alkaloid derivative; Cycloaspidospermidine acetate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (5α,12β,19α,20R)-6,7-Didehydro-1-Methyl-2α,20-Cycloaspidospermidine-3β-Methanol Acetate is produced under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.